Combination of an oncolytic virus with PD-L1 blockade keeps cancer in check.
Combination of an oncolytic virus with PD-L1 blockade keeps cancer in check.
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DOI：
10.1126/scitranslmed.aan2781
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发表时间：
2017-04-19
影响因子：
17.1
通讯作者：
Jonas BA
中科院分区：
文献类型：
--
作者：
Jonas BA
表达CXCL 11的溶瘤牛痘病毒与PD-L1阻断剂的组合显著降低了肿瘤负荷并提高了鼠癌症模型的存活率。
An oncolytic vaccinia virus expressing CXCL11 combined with PD-L1 blockade significantly reduces tumor burden and improves survival in murine cancer models.