Impact of Major Depression and Subsyndromal Symptoms on Quality of Life and Attitudes Toward Aging in an International Sample of Older Adults
Impact of Major Depression and Subsyndromal Symptoms on Quality of Life and Attitudes Toward Aging in an International Sample of Older Adults
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DOI：
10.1093/geront/48.5.593
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发表时间：
2008-10-01
期刊：
影响因子：
5.7
通讯作者：
Power, Mick
中科院分区：
文献类型：
--
作者：
Chachamovich, Eduardo;Fleck, Marcelo;Power, Mick
目的：重度抑郁症对老年人生活质量（QOL）和衰老经历的影响已被报道。研究表明，抑郁症的临床诊断是生活质量的最强预测因子。我们假设，一些调查结果是有偏见的，因为使用不充分的工具。虽然亚综合征抑郁症比重性抑郁症更普遍，但没有关于其对生活质量或对衰老态度的影响的报道。在本研究中，我们的目的是在一个大的国际样本中评估重性和亚综合征抑郁症对生活质量和对衰老的态度的关联。设计和方法：我们的横断面研究评估了来自五大洲20个国家的4，316名受访者。该研究使用了世界卫生组织老年人生活质量（WHOQOL）评估，称为WHOQOL-OLD; WHOQOL工具的简要版本，称为WHOQOL-BREF;以及对老龄化的态度问卷。统计分析包括分层多元回归，以及比较的手段。结果如下：即使是相对轻微的抑郁水平也与所有QOL领域的显著下降以及对衰老的消极态度模式相关（总体WHOQOL-OLD R-2变化= 0.421）。生活质量和对衰老的态度评分随着抑郁强度的增加而降低，即使是在亚综合征水平（总体WHOQOL-OLD平均评分为95.7 vs 86.4，p
Purpose: The impact of major depression on quality of life (QOL) and aging experiences in older adults has been reported. Studies have demonstrated that the clinical diagnosis of major depression is the strongest predictor for QOL. We postulate that some findings are biased because of the use of inadequate instruments. Although subsyndromal depression is more prevalent than major depression, there are no reports on its impact on QOL or attitudes toward aging. In the present study we aim at assessing the association of major and subsyndromal depression on QOL and attitudes toward aging in a large international sample. Design and Methods: Our cross-sectional study assessed 4,316 respondents in 20 countries from five continents. The study used the World Health Organization Quality of Life (WHOQOL) Assessment for Older Adults, known as the WHOQOL-OLD; the brief version of the WHOQOL instrument, known as the WHOQOL-BREF; and the Attitudes to Ageing Questionnaire. Statistical analyses involved hierarchical multiple regression, as well as comparison of means. Results: Even relatively minor levels of depression are associated with a significant decrease in all QOL domains and with a pattern of negative attitudes toward aging (overall WHOQOL-OLD R-2 change =.421). QOL and attitudes toward aging scores are lower as depression intensity is increased, even in subsyndromal levels (overall WHOQOL-OLD mean scores of 95.7 vs 86.4, p