Synergistic effect of a palladium-on-carbon/platinum-on-carbon mixed catalyst in hydrogen/deuterium exchange reactions of alkyl-substituted aromatic compounds
Synergistic effect of a palladium-on-carbon/platinum-on-carbon mixed catalyst in hydrogen/deuterium exchange reactions of alkyl-substituted aromatic compounds
复制标题
DOI：
10.1002/adsc.200606053
复制
发表时间：
2006-06-01
影响因子：
5.4
通讯作者：
Sajiki, Hironao
中科院分区：
文献类型：
--
作者：
Ito, Nobuhiro;Watahiki, Tsutomu;Sajiki, Hironao
在Pd/C-Pt/C-D_2 O-H ~（-2）体系中，烷基取代的芳香族化合物的H-D交换反应存在协同效应。该体系即使在仅由Pd/C或Pt/C独立掺入低氘的位阻位点上也会导致完全的H-D交换结果。由于该反应对多种芳香族化合物具有普适性，因此可应用于聚酰亚胺原料二苯胺衍生物的氘代反应。
We have found a synergistic effect in the H-D exchange reaction of alkyl-substituted aromatic compounds using the Pd/C-Pt/C-D2O-H-2 system. This system would lead to fully H-D exchange results even on the sterically hindered sites which were only low-deuterium incorporated by Pd/C or Pt/C independently. Since the reaction was general for a variety of aromatic compounds, it could be applied to the deuteration of dianiline derivatives as raw materials for polyimides.