Traditional Chinese Exercise for Cardiovascular Diseases: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Traditional Chinese Exercise for Cardiovascular Diseases: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
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DOI:
10.1161/jaha.115.002562
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发表时间:
2016-03-09
影响因子:
5.4
通讯作者:
Niu ZB
Niu ZB
中科院分区:
医学2区
文献类型:
--
作者:
Wang XQ;Pi YL;Chen PJ;Liu Y;Wang R;Li X;Chen BL;Zhu Y;Yang YJ;Niu ZB

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中国传统运动(TCE)被广泛应用于心血管疾病的预防和治疗;然而,关于TCE对心血管疾病患者的益处似乎没有达成共识。这项系统性综述的目的是确定TCE对心血管疾病患者的影响。应用计算机检索PubMed、Embase、Web of Science、Cochrane图书馆、护理及相关卫生文献累计索引、中国国家知识基础设施等相关研究。我们只用随机对照试验涵盖了已发表的文章。结果测量包括生理结果、生化结果、身体功能、生活质量和抑郁。共有35篇文章,2249名心血管疾病患者符合纳入标准。合并分析显示,三氯乙烯可使血压降低9.12 mm·Hg(95%CI−16.38比−1.86,P=0.001),舒张压降低5.12 mm·Hg(95%CI−7.71比−2.52,P<0.001)。患者的甘油三酯(标准化平均差−0.33,95%CI−0.56至−0.09,P=0.006)、6分钟步行试验(平均差59.58m,95%CI−153.13至269.93,P=0.006)、明尼苏达州心力衰竭生活问卷结果(平均差−17.08,95%CI−23.74至−10.41,P<心境状态抑郁量表(−3.02,95%CI−3.50to−2.53,P<0.001)。本研究表明,TCE能有效改善心血管疾病患者的生理结局、生化结局、身体功能、生活质量和抑郁情绪。关于这一主题的更多高质量随机对照试验是有必要的。
Traditional Chinese exercise (TCE) has widespread use for the prevention and treatment of cardiovascular disease; however, there appears to be no consensus about the benefits of TCE for patients with cardiovascular disease. The objective of this systematic review was to determine the effects of TCE for patients with cardiovascular disease. Relevant studies were searched by PubMed, Embase, Web of Science, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature, and the China National Knowledge Infrastructure. We covered only published articles with randomized controlled trials. The outcome measures included physiological outcomes, biochemical outcomes, physical function, quality of life, and depression. A total of 35 articles with 2249 cardiovascular disease patients satisfied the inclusion criteria. The pooling revealed that TCE could decrease systolic blood pressure by 9.12 mm Hg (95% CI −16.38 to −1.86, P=0.01) and diastolic blood pressure by 5.12 mm Hg (95% CI −7.71 to −2.52, P<0.001). Patients performing TCE also found benefits compared with those in the control group in terms of triglyceride (standardized mean difference −0.33, 95% CI −0.56 to −0.09, P=0.006), 6‐minute walk test (mean difference 59.58 m, 95% CI −153.13 to 269.93, P=0.03), Minnesota Living With Heart Failure Questionnaire results (mean difference −17.08, 95% CI −23.74 to −10.41, P<0.001), 36‐Item Short Form physical function scale (mean difference 0.82, 95% CI 0.32–1.33, P=0.001), and Profile of Mood States depression scale (mean difference −3.02, 95% CI −3.50 to −2.53, P<0.001). This study demonstrated that TCE can effectively improve physiological outcomes, biochemical outcomes, physical function, quality of life, and depression among patients with cardiovascular disease. More high‐quality randomized controlled trials on this topic are warranted.