Further exploration of a latent class typology of schizophrenia
Further exploration of a latent class typology of schizophrenia
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DOI：
10.1016/0920-9964(95)00091-7
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发表时间：
1996-05-01
影响因子：
4.5
通讯作者：
Murray, RM
中科院分区：
文献类型：
--
作者：
Sham, PC;Castle, DJ;Murray, RM
我们以前从一个定义的集水区的447名首次接触非情感功能性精神病患者的潜在类分析中得出了精神分裂症的类型学。在这里，使用相同的样本，我们表明，三个亚型，“神经发育”（A型），“偏执”（B型）和“情感障碍”（C型）有不同的发病前，现象学和治疗反应的特点。三种亚型的典型变量分析实现了前两种亚型之间的部分分离，但“情感障碍”类型不太明显。
We previously derived a typology of schizophrenia from a latent class analysis of 447 first-contact non-affective functional psychotic patients from a defined catchment area. Here, using the same sample, we show that the three subtypes, 'neurodevelopmental' (Type A), 'paranoid' (Type B) and 'schizoaffective' (Type C) have different premorbid, phenomenological and treatment response characteristics. A canonical variate analysis of the three subtypes achieved partial separation between the first two subtypes, but the 'schizoaffective' type was less distinct.