Hyperosmotic stress enhances interleukin‐1β expression in Helicobacter pylori‐infected murine gastric epithelial cells in vitro
Hyperosmotic stress enhances interleukin‐1β expression in Helicobacter pylori‐infected murine gastric epithelial cells in vitro
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DOI：
10.1111/j.1440-1746.2006.04293.x
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发表时间：
2006-04
影响因子：
4.1
通讯作者：
Songhua Zhang;A. Yanaka;Masafumi Tauchi;Hideo Suzuki;T. Shibahara;H. Matsui;A. Nakahara;N. Tanaka
中科院分区：
文献类型：
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作者：
Songhua Zhang;A. Yanaka;Masafumi Tauchi;Hideo Suzuki;T. Shibahara;H. Matsui;A. Nakahara;N. Tanaka
背景和目的：胃癌不仅与幽门螺杆菌（H.幽门螺杆菌）感染，但也与摄入高盐饮食。白细胞介素-1 β（IL-1β）在H.幽门螺杆菌感染的胃粘膜本研究的目的是确定高渗应激是否诱导体外胃上皮细胞中IL-1β的表达。
Background and Aim: Gastric cancer is associated not only with Helicobacter pylori (H. pylori) infection, but also with the intake of a high salt diet. Interleukin‐1β (IL‐1β) is highly expressed in H. pylori‐infected gastric mucosa. The aim of the present study was to determine if hyperosmotic stress induces IL‐1β expression in gastric epithelial cells in vitro.