Controlled production of double emulsions in dual-coaxial capillaries device for millimeter-scale hollow polymer spheres
Controlled production of double emulsions in dual-coaxial capillaries device for millimeter-scale hollow polymer spheres
复制标题
双同轴毛细管装置中毫米级空心聚合物球双乳液的控制生产
DOI：
10.1016/j.ces.2013.09.001
复制
发表时间：
2013-12-18
影响因子：
4.7
通讯作者：
Cheng, Yi
中科院分区：
文献类型：
--
作者：
Shao, Ting;Feng, Xuelan;Cheng, Yi
设计并制备了基于毛细管的共流微流控装置，用于控制水包油包水（W/O/W）双乳液液滴的制备，其中溶解在氟苯中的聚苯乙烯用作油相。在实验中采用了两种配置的并流装置。在所谓的一步式装置中，内部毛细管Lip位于中间毛细管Lip的相同横截面处。因此，核液滴和壳液滴同时离开它们的毛细管末端，在一个步骤中形成双乳液液滴。而在所谓的两步装置中，内毛细管尖端位于中间毛细管尖端的上游。核滴和壳滴相继从各自的毛细管末端脱离，分两步形成双乳液滴。在所提出的装置中，流体流速对双乳液液滴尺寸的影响以及它们的形成机理进行了全面的研究。实验结果表明，在设备配置的微小差异将导致显着差异的液滴形成机制，从而尺寸控制律。在两步法装置中，内流对双乳液滴的破碎和外径影响不大，而在一步法装置中，内流对双乳液滴的破碎和外径影响显著。利用制备的双乳液液滴，采用溶剂蒸发法固化复合液滴的油层，得到了毫米级单空腔超薄壳聚合物胶囊。(C)2013爱思唯尔有限公司保留所有权利。
Capillaries-based co-flowing microfluidic devices were designed and then fabricated for the controlled production of water-in-oil-in-water (W/O/W) double-emulsion droplets, where polystyrene dissolved in fluobenzene was employed as the oil phase. Two configurations of the co-flowing devices were employed in the experiments. In the so-called one-step device, the inner capillary Lip locates at the same cross-section of the middle capillary Lip. Thus, the core drop and the shell drop depart from their capillaries ends simultaneously, forming a double-emulsion drop in one step. While in the so-called two step device, the inner capillary tip locates upstream to the middle capillary tip. The core drop and the shell drop break off from their respective capillaries ends successively, forming a double-emulsion drop in two steps. The effect of the fluids now rates on the double-emulsion droplets size as well as their formation mechanism was studied comprehensively in the proposed devices. Experimental results implied that slight difference in device configurations would lead to significant difference in droplet formation mechanisms and thus size-control laws. In the two-step device, the inner stream of fluid had little influence on the breakage and the outer diameter of the double-emulsion drops, while in the one-step device the effect was significant. With the produced double-emulsion droplets, millimeter-sized polymer capsules with single hollow cavity and ultra-thin shells were obtained by solidifying the oil layers of the compound drops using the solvent evaporation method. (C) 2013 Elsevier Ltd. All rights reserved.