Infection Prevalence, Bacterial Loads, and Transmission Efficiency in Oropsylla montana (Siphonaptera: Ceratophyllidae) One Day After Exposure to Varying Concentrations of Yersinia pestis in Blood
Infection Prevalence, Bacterial Loads, and Transmission Efficiency in Oropsylla montana (Siphonaptera: Ceratophyllidae) One Day After Exposure to Varying Concentrations of Yersinia pestis in Blood
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DOI：
10.1093/jme/tjw004
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发表时间：
2016-05-01
影响因子：
2.1
通讯作者：
Eisen, Rebecca J.
中科院分区：
文献类型：
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作者：
Boegler, Karen A.;Graham, Christine B.;Eisen, Rebecca J.
未封闭的跳蚤可以在短时间内传播鼠疫耶尔森氏菌（Yersinia pestis），即引起鼠疫的细菌（= 10（8）cfu/ml）。迄今为止，还没有人确定跳蚤通过EPT获得和传播感染所需的菌血症下限，尽管知道这个阈值对于确定宿主可能感染喂养跳蚤的时间长度至关重要。在此，我们评估的能力，Oropsylla montana（Baker）的收购和传播Y。鼠疫杆菌在进食含有10（3）至10（9）cfu/ml的血液后。我们评估了感染后1天的早期感染率、细菌负荷和传播效率。跳蚤从各种浓度的菌血症血液中获得感染，但只有当跳蚤摄入高度菌血症血液时才观察到传播。
Unblocked fleas can transmit Yersinia pestis, the bacterium that causes plague, shortly (= 10(8) cfu/ml). To date, no one has determined the lower limit of bacteremia required for fleas to acquire and transmit infection by EPT, though knowing this threshold is central to determining the length of time a host may be infectious to feeding fleas. Here, we evaluate the ability of Oropsylla montana (Baker) to acquire and transmit Y. pestis after feeding on blood containing 10(3) to 10(9) cfu/ml. We evaluated the resulting infection prevalence, bacterial loads, and transmission efficiency within the early-phase time period at 1 d postinfection. Fleas acquired infection from bacteremic blood across a wide range of concentrations, but transmission was observed only when fleas ingested highly bacteremic blood.