The influence of volition on breathing-swallowing coordination in healthy adults
The influence of volition on breathing-swallowing coordination in healthy adults
复制标题
DOI：
10.1037/0735-7044.121.6.1174
复制
发表时间：
2007-12-01
影响因子：
1.9
通讯作者：
Carroll, Grant J.
中科院分区：
文献类型：
--
作者：
Kelly, Bronwen N.;Huckabee, Maggie-Lee;Carroll, Grant J.
这项研究旨在阐明皮质调节在协调呼吸和吞咽中的作用。使用颏下表面肌电图、鼻气流和甲状腺声学的时间锁定记录来评估 20 名健康成年人在 3 种情况下的非营养性呼吸吞咽协调 (BSC) 和吞咽呼吸暂停持续时间 (SAD)。这些条件代表了基于皮质激活水平降低的意志性至非意志性吞咽控制的连续体：清醒期间自愿发起的吞咽、清醒时非自愿的吞咽以及睡眠期间反射性发起的吞咽。无论唤醒水平如何，在有意识和无意识条件下，吸气和呼气之间的吞咽比例不同。 SAD 不随条件而改变。总之，平衡计分卡受意志程度的影响，但不受唤醒水平的影响。这意味着皮质对 BSC 的影响仅限于自愿启动吞咽的情况，并间接涉及补充运动皮质或岛叶皮质的募集。 SAD 在各种条件下保持稳定，因此可以认为相对不受球上影响。
This research was designed to clarify the role of cortical modulation in the coordination of respiration and swallowing. Time-locked recordings of submental surface electromyography, nasal airflow, and thyroid acoustics were used to evaluate nonnutritive breathing-swallowing coordination (BSC) and swallowing apnea duration (SAD) of 20 healthy adults during 3 conditions. These conditions represented a continuum of volitional through nonvolitional swallowing control on the basis of a decreasing level of cortical activation: voluntarily initiated swallows during wakefulness, nonvolitional awake swallows, and reflexively initiated swallows during sleep. Differing proportions of swallows at the cusps between inspiration and expiration were found between the volitional and nonvolitional conditions, irrespective of the level of arousal. SAD was unaltered by condition. In conclusion, BSC is influenced by degree of volition but not by level of arousal. This implies that cortical influence on BSC is limited to conditions in which swallowing is voluntarily initiated and indirectly implicates the recruitment of the supplementary motor or insular cortices. SAD remained stable across conditions and may therefore be considered relatively impervious to suprabulbar influence.