High Resolution X-ray-Induced Acoustic Tomography.
High Resolution X-ray-Induced Acoustic Tomography.
复制标题
高分辨率 X 射线诱导声学断层扫描。
DOI：
10.1038/srep26118
复制
发表时间：
2016-05-18
影响因子：
4.6
通讯作者：
Xing L
中科院分区：
文献类型：
--
作者：
Xiang L;Tang S;Ahmad M;Xing L
基于吸收的CT成像已经成为医学诊断、生物学和材料科学中的宝贵工具。然而，CT需要大量的投影数据和高辐射剂量来实现上级图像质量。在这封信中，我们报告了一种新的成像方式，X射线诱导声断层扫描（XACT），它利用了高灵敏度的X射线吸收和高超声分辨率在一个单一的模式。单次投影X射线曝光足以在3D空间中生成声信号，因为X射线生成的声波具有球形性质并且从它们的生成点在所有方向上传播。我们证明了金基准标记的成功重建，空间分辨率约为350 μm。XACT揭示了一种新的成像机制，并为X射线结构测定提供了前所未有的机会。
Absorption based CT imaging has been an invaluable tool in medical diagnosis, biology, and materials science. However, CT requires a large set of projection data and high radiation dose to achieve superior image quality. In this letter, we report a new imaging modality, X-ray Induced Acoustic Tomography (XACT), which takes advantages of high sensitivity to X-ray absorption and high ultrasonic resolution in a single modality. A single projection X-ray exposure is sufficient to generate acoustic signals in 3D space because the X-ray generated acoustic waves are of a spherical nature and propagate in all directions from their point of generation. We demonstrate the successful reconstruction of gold fiducial markers with a spatial resolution of about 350 μm. XACT reveals a new imaging mechanism and provides uncharted opportunities for structural determination with X-ray.