MYOPIA AND INTELLIGENCE - A PLEIOTROPIC RELATIONSHIP
MYOPIA AND INTELLIGENCE - A PLEIOTROPIC RELATIONSHIP
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DOI：
10.1007/bf00451456
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发表时间：
1988-09-01
期刊：
影响因子：
5.3
通讯作者：
JENSEN, AR
中科院分区：
文献类型：
--
作者：
COHN, SJ;COHN, CMG;JENSEN, AR
在一般人群中，近视和上级智力之间的关系已经得到了很好的证实，我们在一组智力天才儿童和他们的智力较低的同胞兄弟姐妹中进行了调查，以确定近视和心理测量智力的关系是否与多效性假说一致，即，这两种特征都受同一基因或一组基因的影响。如果不能在智力天赋异禀和智力天赋低下的兄弟姐妹之间找到近视程度的差异（作为一个度量变量），就会与多效性相矛盾。在文献中已经假设了各种可能的因果途径，包括遗传和环境，以解释智力和近视之间的关系，这些仍然不能排除。然而，在理论上值得注意的是，鉴于智力和近视具有相当大的遗传力的独立证据，本研究中发现的高度显著的资优-非资优同胞近视差异与智力和近视多效性相关的假设是一致的。
The well-established association between myopia and superior intelligence in the general population was investigated in a group of intellectually gifted children and their less gifted full siblings to determine whether the relationship of myopia to psychometric intelligence is consistent with the hypothesis of pleiotropy, i.e., both characteristics are affected by the same gene or set of genes. Failure to find a difference in degree of myopia, assessed as a metric variable, between intellectually gifted and nongifted siblings would contradict pleitropy. A variety of possible causal pathways, both genetic and environmental, have been hypothesized in the literature to explain the relationship between intelligence and myopia, and these still cannot be ruled out. It is theoretically noteworthy, however, in view of the independent evidence for the considerable heritability of both intelligence and myopia, that the highly significant gifted-nongifted sibling difference in myopia found in the present study is consistent with the hypothesis that intelligence and myopia are related pleiotropically.