EFFECTS OF EARLY EXPERIENCE ON ADRENOCORTICAL REACTIVITY
EFFECTS OF EARLY EXPERIENCE ON ADRENOCORTICAL REACTIVITY
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DOI：
10.1016/0031-9384(69)90179-6
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发表时间：
1969-01-01
影响因子：
2.9
通讯作者：
GROTA, LJ
中科院分区：
文献类型：
--
作者：
ADER, R;GROTA, LJ
未操作的对照动物和大鼠在断奶前或断奶后受到处理或电击，随后通过将其置于新环境中 5 秒或 3 分钟进行刺激。在该刺激停止后5、15或30分钟以及未接受此类刺激的动物中对血浆皮质酮水平进行采样。处理过的动物和电击过的动物没有区别。然而，作为一个群体，被操纵的动物的皮质酮反应表明，无论刺激的持续时间如何，它们的反应性都低于对照组。
Unmanipulated control animals and rats that were exposed to handling or electric shock either pre- or post-weaning were subsequently stimulated by being placed into a novel environment for 5 sec or 3 min. Plasma corticosterone levels were sampled 5, 15, or 30 min following the cessation of this stimulation and in animals that received no such stimulation. The handled and shocked animals did not differ. As a group, however, the corticosterone response of the manipulated animals showed them to be less reactive than controls irrespective of the duration of stimulation.