Local Emergence of a del HV69-70 SARS-CoV-2 Variant in Burgundy, France.
Local Emergence of a del HV69-70 SARS-CoV-2 Variant in Burgundy, France.
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DOI:
10.3390/pathogens11020124
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发表时间:
2022-01-20
期刊:
影响因子:
--
通讯作者:
Manoha C
中科院分区:
文献类型:
--
作者:
Giraudon H;Djemai M;Auvray C;de Rougemont A;Belliot G;Bour JB;Manoha C
In the autumn of 2020, a short-lived epidemic of a spike del69-70 deletion variant of SARS-CoV-2 was identified, with most cases (n = 95) found in Montceau-les-Mines, France. This spike gene target failure (SGTF) variant spread quickly in nursing homes. The Alpha variant, which also harbors this deletion, appeared in Burgundy in January 2021 after the disappearance of the Montceau-les-Mines del69-70 variant. Our findings illustrate the risk of the fast spread of geographically isolated variants and reinforce the need for the continuous tracking of outbreaks. In some cases, these studies may reveal emerging variants that affect public health or vaccine development.
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