[Survey of triamcinolone-related non-infectious endophthalmitis].
[Survey of triamcinolone-related non-infectious endophthalmitis].
复制标题
曲安奈德相关非感染性眼内炎的调查[J].
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
H. Yamashita
中科院分区：
文献类型：
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作者：
T. Sakamoto;T. Ishibashi;Y. Ogura;F. Shiraga;S. Takeuchi;H. Yamashita
目的
调查日本与曲安奈德 (TA) 治疗眼部疾病相关的非感染性眼内炎。
主题和方法
我们向日本视网膜和玻璃体学会的 24 名委员会成员发送了一份调查问卷，要求提供有关 2009 年 1 月至 12 月期间玻璃体内注射 TA 相关非感染性眼内炎的信息。该调查特别涵盖了玻璃体内注射和玻璃体切除术术中注射 TA 的情况。
结果
所有 24 名成员均对涉及 562 只眼睛的活体 TA 使用的调查做出了回应；糖尿病性黄斑水肿 325 只眼，视网膜静脉阻塞 118 只眼，葡萄膜炎 91 只眼，年龄相关性黄斑变性 11 只眼，辅助使用视网膜光凝术 17 只眼。 6973 只眼睛在术中使用了玻璃体可视化技术。玻璃体内 TA 后 9 只眼（1.6%）发生非感染性眼内炎，术中 TA 后 7 只眼（0.1%）发生非感染性眼内炎。最常见的症状是视力模糊，无疼痛或轻度结膜充血。术后第二天开始突然出现严重的前房和玻璃体炎症，但自行消失，无并发症。
结论
结果发现玻璃体内TA后发生非感染性眼内炎。尽管视力预后良好，但视网膜专家应认识到这种并发症。
PURPOSE
To survey non-infectious endophthalmitis related to triamcinolone acetonide (TA) for ocular diseases in Japan.
SUBJECTS AND METHODS
A questionnaire was sent to the 24 committee members of the Japanese Retina and Vitreous Society requesting information regarding non-infectious endophthalmitis related to intravitreous TA administered from January through December 2009. The survey specifically covered the use of TA in intravitreal injections and intraoperatively during vitrectomy procedures.
RESULTS
All 24 members responded to the survey involving intraviteal TA use in 562 eyes; 325 eyes for diabetic macular edema, 118 eyes for retinal vein occlusion, 91 eyes for uveitis, 11 eyes for age-related macular degeneration and 17 eyes had adjunctive use in retinal photocoagulation. Intraoperative use for visualizing vitreous was done in 6973 eyes. Noninfectious endophthalmitis occurred in 9 eyes (1.6%) after intravitreous TA and 7 eyes (0.1%) after intraoperative TA. The most frequent symptom was blurred vision with no pain or mild conjunctival injection. Sudden severe anterior chamber and vitreous inflammation occurred beginning on the day following surgery, but it disappeared spontaneously without complications.
CONCLUSIONS
It was found that non-infectious endophthalmitis occurred after intravitreous TA. Although the visual prognosis is good, this complication should be recognized by retina specialists.