Early bactericidal activity of high-dose rifampin in patients with pulmonary tuberculosis evidenced by positive sputum smears
Early bactericidal activity of high-dose rifampin in patients with pulmonary tuberculosis evidenced by positive sputum smears
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DOI：
10.1128/aac.01474-06
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发表时间：
2007-08-01
影响因子：
4.9
通讯作者：
Donald, P. R.
中科院分区：
文献类型：
--
作者：
Diacon, A. H.;Patientia, R. F.;Donald, P. R.
我们研究了两倍标准剂量的利福平对涂片呈阳性的肺结核受试者的早期杀菌活性。观察到的平均 2 天活性几乎是标准剂量报告的两倍。需要进一步的研究来确定较高的利福平剂量是否有助于缩短结核病治疗时间。
We studied the early bactericidal activity of twice the standard dose of rifampin in subjects with pulmonary tuberculosis evidenced by positive smears. The observed mean 2-day activity was almost double that reported at the standard dose. Further studies are warranted to establish whether higher rifampin doses might assist in shortening tuberculosis treatment.