Ageing reduces sympatho-suppressive response to head-out water immersion in humans.
Ageing reduces sympatho-suppressive response to head-out water immersion in humans.
复制标题
衰老会降低人类对头浸水的交感神经抑制反应。
DOI：
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复制
发表时间：
1996
期刊：
影响因子：
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通讯作者：
K. Koga
中科院分区：
文献类型：
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作者：
C. Miwa;T. Mano;M. Saito;S. Iwase;T. Matsukawa;Y. Sugiyama;K. Koga
肌肉交感神经活动(MSNA)在热中频头部水浸泡(HOI)期间受到抑制。在本研究中，确定了老化对MSNA对HOI的抑制反应的影响。16例健康男性，10例19~30岁(青年组)，6例45~67岁(老年组)。在HOI期间，所有受试者的MSNA均被抑制。与年轻组相比，老年组的抑制反应明显不明显。年龄与HOI引起的MSNA抑制反应呈显著负相关(r=-0.53，P<；0.05)。我们得出结论：交感神经活动对HOI的抑制反应随年龄增长而减弱。
Muscle sympathetic nerve activity (MSNA) is suppressed during thermoneutral head-out water immersion (HOI) in humans. In this study, the effects of ageing on the suppressive response of MSNA to HOI were determined. MSNA was recorded microneurographically from the tibial nerve in 16 healthy men, 10 of whom were aged 19-30 years (young group) and six aged 45-67 years (older group). MSNA was suppressed in all the subjects during HOI. The suppressive response was significantly less prominent in the older group than in the young group. A significant negative correlation between age and the suppressive response of MSNA induced by HOI (r = -0.53, P < 0.05) was found. We conclude that suppressive response of sympathetic nerve activity to HOI is reduced with age.