Genetic, geographic, and linguistic variation among South American Indians: Possible sex influence
Genetic, geographic, and linguistic variation among South American Indians: Possible sex influence
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DOI：
10.1002/ajpa.10015
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发表时间：
2002-01-01
影响因子：
2.8
通讯作者：
Salzano, FM
中科院分区：
文献类型：
--
作者：
Fagundes, NJR;Bonatto, SL;Salzano, FM
为了更好地了解南美人的遗传变异性、地理距离和语言联系之间的关系，并阐明性别迁移率是否相同，对四组群体和等位基因(组1：48个群体，12个等位基因；组2：16个(均属于图皮语组)和12个；组3：21和17个；组4：28个和4个单倍型)进行了空间自相关、Mantel检验和FST分析。组1-3包括血型和蛋白(即血清蛋白、红细胞酶和免疫球蛋白系统)，而组4仅涉及线粒体DNA(MtDNA)。后一组也接受了分子方差分析(AMOVA)评估。当考虑到血型和蛋白质系统时，有统计学意义的相关图的频率低于其他人群，但4个mtDNA单倍群中有3个给出了群体结构的建议。当地理位置保持不变时，这种细胞器的变异性也与语言显著相关。每一代的迁移率一般较低，但对女性的估计较高。AMOVA的结果表明，成员说相同语言的群体在基因上是相同的，可以被视为这一分析水平的最终进化单位。Am J Phys Anthropol117：68-78,2002.(C)2002年Wiley-Liss，Inc.
To better understand the relationship between genetic variability, geographical distance, and linguistic affiliation in South Amerinds, and to elucidate whether the migration rate is the same for both sexes, spatial autocorrelation, Mantel's test, and FST analyses were performed in four sets of populations and alleles (group 1: 48 populations, 12 alleles; group 2: 16 (all belonging to the Tupi linguistic group) and 12; group 3: 21 and 17; and group 4: 28 and 4 haplotypes). Groups 1-3 included blood group and protein (i.e., serum protein, red cell enzymes, and immunoglobulin systems), while group 4 was concerned with mitochondrial DNA (mtDNA) only. The latter set was also subjected to a molecular analysis of variance (AMOVA) evaluation. The frequencies of statistically significant correlograms were lower than those obtained in other populations when the blood groups and protein systems were considered, but 3 of the 4 mtDNA haplogroups gave suggestions of population structure. The variability in this organelle is also significantly correlated with language when geography is held constant. Migration per generation is generally low, but higher estimates were obtained for females. The AMOVA results suggest that populations whose members speak the same language are genetically homogeneous and may be viewed as the ultimate evolutionary unit at this level of analysis. Am J Phys Anthropol 117:68-78, 2002. (C) 2002 Wiley-Liss, Inc.