Cationic surfactant changes the morphology of DNA molecules.
Cationic surfactant changes the morphology of DNA molecules.
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DOI：
10.1021/la051443p
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发表时间：
2007-01
期刊：
影响因子：
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通讯作者：
H. Nakanishi;K. Tsuchiya;T. Okubo;H. Sakai;M. Abe
中科院分区：
文献类型：
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作者：
H. Nakanishi;K. Tsuchiya;T. Okubo;H. Sakai;M. Abe
研究了阳离子表面活性剂十六烷基三甲基溴化铵（CTAB）在一定温度下对水中DNA分子聚集形式的影响。在临界胶束浓度（CMC）以下，随着浓度的增加，CTAB使DNA分子的聚集形式发生变化，从松散的球形到棒状再到环状。这种变化可能是由于静电相互作用导致CTAB与DNA分子之间形成离子络合物，从而降低了后者的表面电荷和在水中的溶解度。
The effect of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, was investigated on the aggregated form of DNA molecules in water at a given temperature. CTAB caused changes in the aggregated form of DNA molecules from loosely packed spherical to rodlike through toroidal one with increasing concentration below the critical micelle concentration (CMC). The change was suggested to arise from the ion complex formation between CTAB and DNA molecules due to the electrostatic interaction, thereby reducing the surface charge and solubility in water of the latter.