Health and Disease at Age 100
Health and Disease at Age 100
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DOI：
10.3238/arztebl.2016.0203
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发表时间：
2016-03-25
影响因子：
7.7
通讯作者：
Rott, Christoph
中科院分区：
文献类型：
--
作者：
Jopp, Daniela S.;Boerner, Kathrin;Rott, Christoph
背景：来自世界各地的百岁老人研究表明，活到100岁通常会带来严重的健康问题。本研究通过描述德国百岁老人的健康状况，增加了来自其他国家的现有知识。方法：在第二次海德堡百岁老人研究中，共有112名百岁老人或他们的主要接触者提供了关于急慢性健康状况和疼痛的信息(平均年龄=100.45岁，标准差[SD]=0.47，89%女性)。结果：参与者表现出很高的共病，平均5种疾病(平均值=5.3；SD=2.2)。患病率最高的健康状况是感觉(视觉、听力；94%)、活动(72%)和肌肉骨骼状况(60%)。心血管疾病(57%)和泌尿系统疾病(55%)也很常见。30%的参与者经常感受到疼痛。在报告疼痛的人中，36%的人表示疼痛超过了可承受的水平。结论：德国百岁老人经历了大量的疾病，主要是感觉和活动方面的问题。心血管疾病是发病率较高的唯一可能致命的疾病。未解决的疼痛的证据似乎令人担忧，需要进一步的研究。新出现的健康状况表明，即使在非常高龄的时候，通过加强诊断和优化疾病管理，生活质量也可能得到改善。可通过预防性努力解决行动限制问题。
Background: Centenarian studies from around the world have shown that reaching age 100 typically involves substantial health issues. The present study adds to the existing knowledge from other countries by describing health conditions in German centenarians.Methods :A total of 112 centenarians or their primary contacts provided information on acute and chronic health conditions and pain in the context of the Second Heidelberg Centenarian Study (mean age = 100.45 years, standard deviation [SD] = 0.47, 89% females).Results: Participants showed high comorbidity, with an average of five illnesses (mean = 5.3; SD = 2.20). Health conditions with highest prevalence were sensory (vision, hearing; 94%), mobility (72%) and musculoskeletal conditions (60%). Cardiovascular conditions (57%) and urinary system ailments (55%) were also common. Pain was experienced often by 30% of the participants. Of those reporting any pain, 36% indicated pain exceeding bearable levels.Conclusion: German centenarians experienced a substantial number of illnesses, dominated by sensory and mobility conditions. Cardiovascular diseases were the only potentially lethal illnesses with high prevalence. Evidence of unaddressed pain seems alarming, requiring future research. Emerging health profiles indicate that even in very advanced age, quality of life may be improved by enhanced diagnostics and optimal disease management. Mobility limitations may be addressed with preventive efforts.