A Systematic Review of the Tensile Biomechanical Properties of the Neonatal Brachial Plexus
A Systematic Review of the Tensile Biomechanical Properties of the Neonatal Brachial Plexus
复制标题
新生儿臂丛神经拉伸生物力学特性的系统评价
DOI：
10.1115/1.4051399
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Singh, Anita
中科院分区：
文献类型：
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作者：
Orozco, Virginia;Magee, Rachel;Balasubramanian, Sriram;Singh, Anita
据报道，臂丛神经（BP）产伤的发生率为每1000例活产1至4例。在复杂的分娩过程中，新生儿，产妇和其他与分娩有关的因素可能会导致新生儿臂丛神经过度拉伸或撕脱，导致损伤。了解新生儿臂丛神经在拉伸时的生物力学反应可以提供对损伤结果的了解，同时指导预防性操作的发展，有助于减少新生儿臂丛神经损伤的发生。这篇综述文章的目的是提供一个全面的概述现有的文献报告臂丛神经的生物力学反应，在成人和新生儿，当受到拉伸。尽管报道的臂丛神经生物力学特性存在差异，但现有研究证实了臂丛神经组织的加载速率和加载方向依赖性。未来的研究，可能在体内，利用临床相关的新生儿大动物模型，可以提供新生儿臂丛神经的生物力学参数的平移失败值时，受到拉伸。
Brachial plexus (BP) birth injury has a reported incidence of 1 to 4 per 1000 live births. During complicated deliveries, neonatal, maternal, and other birth-related factors can cause over-stretching or avulsion of the neonatal brachial plexus leading to injury. Understanding biomechanical responses of the neonate brachial plexus when subjected to stretch can offer insight into the injury outcomes while guiding the development of preventative maneuvers that can help reduce the occurrence of neonatal brachial plexus injuries. This review article aims to offer a comprehensive overview of existing literature reporting biomechanical responses of the brachial plexus, in both adults and neonates, when subjected to stretch. Despite the discrepancies in the reported biomechanical properties of the brachial plexus, available studies confirm the loading rate and loading direction dependency of the brachial plexus tissue. Future studies, possibly in vivo, that utilize clinically relevant neonatal large animal models can provide translational failure values of the biomechanical parameters for the neonatal brachial plexus when subjected to stretch.