Zinc Content in Breast Milk and Its Association with Maternal Diet
Zinc Content in Breast Milk and Its Association with Maternal Diet
复制标题
DOI：
10.3390/nu10101438
复制
发表时间：
2018-10-01
期刊：
影响因子：
5.9
通讯作者：
Borisova, Anastasija
中科院分区：
文献类型：
--
作者：
Aumeistere, Liva;Ciprovica, Inga;Borisova, Anastasija
背景：锌是一种不可缺少的元素，参与许多生物过程。相应地，青少年时期锌摄入不足会对成长中的身体功能产生不利影响。本研究的目的是确定拉脱维亚哺乳期妇女母乳中的锌含量以及影响其的因素（母亲饮食、母亲和婴儿的特征、母乳喂养方式）。方法：24 小时内总共收集并汇集了 62 份成熟乳（产后至少 1 个月）样本。使用电感耦合等离子体质谱法（ICP-MS；Agilent 7700x，Agilent Technologies，东京，日本）测定锌含量（mg 100 mL(-1)）。结果：成熟母乳中锌的含量范围为0.01至0.34 mg·100 mL(-1)，中位数（四分位数范围）含量为0.10（0.05-0.15）mg·100 mL(-1)。产后时间是母乳中锌含量的显着负预测因子（r = -0.500；p = 0.000）。母亲锌摄入量中位数为 10.70 (7.24-15.27) 毫克。然而，母乳中的锌含量不受母亲膳食锌摄入量的影响（r = 0.155；p = 0.221）。结论：母亲膳食锌摄入量接近哺乳期妇女的推荐摄入量（11 毫克），但由于母乳中锌含量较低，拉脱维亚婴儿可能无法摄入足够的锌。未来的研究应该旨在通过评估母亲和婴儿的血浆或血清水平来评估锌状况。
Background: Zinc is an indispensable element, being involved in many biological processes. Correspondingly, insufficient zinc intake in early youth can detrimentally affect the function of a growing body. The aim of this study was to determine zinc content in breast milk among lactating women in Latvia and factors (maternal diet; mother's and baby's characteristics; breastfeeding pattern) affecting it. Methods: In total, 62 mature milk (at least one month postpartum) samples were collected and pooled within 24 h. Zinc content (mg 100 mL(-1)) was determined using inductively coupled plasma mass spectrometry (ICP-MS; Agilent 7700x, Agilent Technologies, Tokyo, Japan). Results: Zinc content in mature breast milk ranged from 0.01 to 0.34 mg 100 mL(-1) with a median (interquartile range) content of 0.10 (0.05-0.15) mg 100 mL(-1). Time postpartum was a significant negative predictor for zinc content in breast milk (r = -0.500; p = 0.000). Median maternal zinc intake was 10.70 (7.24-15.27) mg. Yet, zinc content in breast milk was unaffected by maternal dietary zinc intake (r = 0.155; p = 0.221). Conclusions: Maternal dietary zinc intake was nearly the recommended intake for lactating women (11 mg), but due to low zinc content in breast milk, babies in Latvia might not receive sufficient zinc intake. Future research should aim for the assessment of zinc status by evaluating plasma or serum levels of both mothers and babies.