Comb-shaped poly(ethylene glycol)-modified subtilisin Carlsberg is soluble and highly active in ionic liquids
Comb-shaped poly(ethylene glycol)-modified subtilisin Carlsberg is soluble and highly active in ionic liquids
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DOI：
10.1039/b505479f
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发表时间：
2005-01-01
影响因子：
4.9
通讯作者：
Goto, M
中科院分区：
文献类型：
--
作者：
Nakashima, K;Maruyama, T;Goto, M
枯草杆菌蛋白酶嘉士伯共轭梳形聚（乙二醇）在普通的离子液体中溶解，而不加水，并表现出较高的酯交换活性的离子液体，[Tm][Tf 2N]，比在有机溶剂中常用的酶生物转化。
Subtilisin Carlsberg conjugated with comb-shaped poly( ethylene glycol) was solubilized in common ionic liquids without adding water, and exhibited higher transesterification activity in an ionic liquid, [Emim][Tf2N], than in organic solvents commonly used for enzymatic biotransformation.