Spectroscopic and biological approach in the characterization of Cr(III), Mn(II) and Co(II) complexes with a novel hexaazamacrocyclic ligand derived from semicarbazide
Spectroscopic and biological approach in the characterization of Cr(III), Mn(II) and Co(II) complexes with a novel hexaazamacrocyclic ligand derived from semicarbazide
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光谱和生物学方法表征具有源自氨基脲的新型六氮杂大环配体的 Cr(III)、Mn(II) 和 Co(II) 配合物
DOI：
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
A. Gautam
中科院分区：
文献类型：
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作者：
S. Chandra;A. Gautam
合成了Cr（III）、Mn（II）和Co（II）与新型5,7,12,14-四苯基-1,2,4,8,10,11-六氮杂环十四烷-3,9-二酮大环配体THTD (L)的配合物，并通过元素分析、摩尔电导和磁化率测量、质量、1h - nmr、IR、电子和EPR光谱研究对其进行了表征。基于光谱研究，确定了Cr（III）、Mn（II）和Co（II）配合物的八面体结构。体外筛选了该配体及其配合物对几种细菌和植物病原真菌的抑制作用。这些金属配合物被发现是比它们所衍生的自由配体更有效的抗菌剂。
Complexes of Cr(III), Mn(II) and Co(II) with a novel 5,7,12,14-tetraphenyl-1,2,4,8,10,11-hexaazacyclotetradecane-3,9-dione macrocyclic ligand, THTD (L), were synthesized and characterized by elemental analysis, molar conductance and magnetic susceptibility measurements, as well as by mass, 1 H-NMR, IR, electronic and EPR spectral studies. Based on the spectral studies, an octahedral geometry was assigned for the Cr(III), Mn(II) and Co(II) complexes. The ligand and its complexes were screened in vitro against some species of bacteria and plant pathogenic fungi. The metal complexes were found to be more active antimicrobial agents than the free ligand from which they were derived.