Timeliness and completeness of laboratory-based surveillance of COVID-19 cases in England.
Timeliness and completeness of laboratory-based surveillance of COVID-19 cases in England.
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DOI：
10.1016/j.puhe.2021.03.012
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发表时间：
2021-05
期刊：
影响因子：
5.2
通讯作者：
Dabrera G
中科院分区：
文献类型：
--
作者：
Clare T;Twohig KA;O'Connell AM;Dabrera G
该研究的目的是使用患者水平的数据，评估英国迅速发展的严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）感染监测的完整性和及时性。这是一项观察性研究，对公共卫生监测系统进行评估。英格兰公共卫生第二代监测系统通过常规实验室报告程序以及与商业伙伴合作加强测试收集数据。选择了三个时期来介绍英国第一波大流行前后疾病监测的发展。总结了关键人口统计学和流行病学领域有效条目的完整性。使用记录的日期间隔评估时间：从样本采集到实验室报告阳性结果，国家监测系统收到阳性结果，以及可用于流行病学分析的数据。在每个时期，人口统计学变量的完整性超过95%，增强的种族超过85%，从而可以丰富地了解英格兰COVID-19病例的一般特征。在采集标本后3天内完成国家系统所有报告阶段的病例比例从第1阶段的69.1%增加到第3阶段的76.6%。在第3阶段，完成所有报告阶段的中位天数从以前的3天减少到2天。对每一报告阶段的分析提供了暗示性证据，表明随着时间的推移，报告制度的及时性有所提高。一旦国家系统收到用于流行病学的数据，就立即进行一致和迅速的处理。及时性方面的延迟最有可能发生在报告过程的第一阶段，即实验室输入监测平台之前。在应对期间得到加强的现有国家监测机制成功地提供了病例数据的快速收集和报告，以促进流行病学监测和分析，并指导公共卫生政策和战略。
The aim of the study was to evaluate completeness and timeliness of the rapidly developed surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in England using patient-level data. This is an observational study wherein public health surveillance systems are evaluated. Data were collected in the Public Health England's Second-Generation Surveillance System through routine laboratory reporting processes, as well as via enhanced testing in collaboration with commercial partners. Three periods were chosen to present developments in disease surveillance around the first pandemic wave in England. Completeness of valid entries for key demographic and epidemiological fields was summarised. Timeliness was assessed using recorded date intervals: from sample collection to the laboratory reporting a positive result, the positive result being received by the national surveillance system and the data being available for epidemiological analysis. In each period, demographic variables were more than 95% complete and enhanced ethnicity more than 85%, allowing a rich understanding of the general characteristics of COVID-19 cases in England. The proportion of cases completing all reporting stages of the national system within 3 days of when the specimen was taken increased from 69.1% in period 1 to 76.6% in period 3. In period 3, the median number of days to complete all reporting stages decreased to 2, from 3 in previous periods. Analysis of each reporting stage offers suggestive evidence that timeliness of the system has improved as reporting has become established over time. Timely processing of data for epidemiological use was consistent and rapid once received by the national system. Delays in timeliness were most likely to occur in the first stage of the reporting process, before laboratory input to the surveillance platform. Existing national surveillance mechanisms enhanced during the response have succeeded in providing rapid collection and reporting of case data to facilitate epidemiological monitoring and analysis and guide public health policy and strategy.
DOI：
10.1016/s1473-3099(20)30984-1
发表时间：
2021-04
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Davies NG;Barnard RC;Jarvis CI;Russell TW;Semple MG;Jit M;Edmunds WJ;Centre for Mathematical Modelling of Infectious Diseases COVID-19 Working Group;ISARIC4C investigators
通讯作者：
ISARIC4C investigators
DOI：
10.1016/j.jinf.2021.02.022
发表时间：
2021-04
期刊：
The Journal of infection
影响因子：
--
作者：
Mensah AA;Sinnathamby M;Zaidi A;Coughlan L;Simmons R;Ismail SA;Ramsay ME;Saliba V;Ladhani SN
通讯作者：
Ladhani SN
影响因子：
4.2
作者：
Holden, B.;Quinney, A.;Gent, M.
通讯作者：
Gent, M.