Rigor and reproducibility in polymer nanoparticle synthesis and characterization.
Rigor and reproducibility in polymer nanoparticle synthesis and characterization.
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DOI：
10.1039/c9ra10091a
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发表时间：
2020
期刊：
影响因子：
3.9
通讯作者：
Benoit DSW
中科院分区：
文献类型：
--
作者：
Sims KR Jr;Maceren JP;Strand AI;He B;Overby C;Benoit DSW
使用标准化的工艺改进方法和工具来提高二嵌段共聚物纳米颗粒（NP）合成和表征的精确性和再现性。将设计参数与NP特性联系起来的模型促进了NP合成的过程控制，这可能会促进NP研究的转化和商业化。新的建模和过程控制方法提供了有用的见解，以提高聚合物纳米颗粒合成和表征的严谨性和再现性。
Standardized process improvement methods and tools were used to enhance the rigor and reproducibility of diblock copolymer nanoparticle (NP) synthesis and characterization. Models linking design parameters with NP characteristics boosted process control for NP synthesis, which may improve translation and commercialization of NP research. Novel modeling and process control approaches provide useful insights to improve rigor and reproducibility in polymer nanoparticle synthesis and characterization.