Towards an emotional 'stress test': a reliable, non-subjective cognitive measure of anxious responding.
Towards an emotional 'stress test': a reliable, non-subjective cognitive measure of anxious responding.
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朝着情感上的“压力测试”：一种可靠的，非主体的认知度量的焦虑响应。
DOI：
10.1038/srep40094
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发表时间：
2017-01-10
影响因子：
4.6
通讯作者：
Robinson OJ
中科院分区：
文献类型：
--
作者：
Aylward J;Robinson OJ
对压力或外部威胁的反应是情绪和焦虑障碍病因学的关键因素。目前对威胁的焦虑反应的测量是有限的，因为它们主要依赖于回顾性的自我报告。客观地量化威胁反应的个体差异将是提高我们对焦虑症脆弱性理解的重要一步。因此，我们的目标是开发一种可靠、客观、受试者内部的焦虑反应“压力测试”。为此，我们从基线到2-4周（n = 50）和5-9个月后（n = 22）再次检查了威胁增强在抑制控制任务中的表现。我们还描述了更大样本（n = 157）的单次会话数据，以提供更好的总体水平的任务绩效方差估计。重复先前的研究结果，电击的威胁提高了干扰物的准确性，减慢了我们任务中目标的反应时间。至关重要的是，受试者内部焦虑自我报告测量（ICC = 0.66）和威胁增强任务表现（ICC = 0.58）都显示出临床有用的重测信度。因此，威胁增强的任务表现可能将承诺作为个体焦虑反应的非主观衡量标准。
Response to stress or external threats is a key factor in mood and anxiety disorder aetiology. Current measures of anxious responding to threats are limited because they largely rely on retrospective self-report. Objectively quantifying individual differences in threat response would be a valuable step towards improving our understanding of anxiety disorder vulnerability. Our goal is to therefore develop a reliable, objective, within-subject ‘stress-test’ of anxious responding. To this end, we examined threat-potentiated performance on an inhibitory control task from baseline to 2–4 weeks (n = 50) and again after 5–9 months (n = 22). We also describe single session data for a larger sample (n = 157) to provide better population-level estimates of task performance variance. Replicating previous findings, threat of shock improved distractor accuracy and slowed target reaction time on our task. Critically, both within-subject self-report measures of anxiety (ICC = 0.66) and threat-potentiated task performance (ICC = 0.58) showed clinically useful test-retest reliability. Threat-potentiated task performance may therefore hold promise as a non-subjective measure of individual anxious responding.