Anxiety disorders in patients with Parkinson's disease.
Anxiety disorders in patients with Parkinson's disease.
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帕金森病患者的焦虑症。
DOI：
10.1176/ajp.147.2.217
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Uhde Tw
中科院分区：
文献类型：
--
作者：
Murray B. Stein;Heuser Ij;Juncos Jl;Uhde Tw
为了研究焦虑障碍在特发性帕金森病患者中的患病率和重要性，作者系统地评估了24例帕金森病患者是否存在DSM-III-R轴I综合征。9例受试者（38%）患有具有临床意义的当前焦虑障碍。焦虑的严重程度与帕金森症状的严重程度、左旋多巴暴露的累积时间或左旋多巴的当前剂量无关。这些发现表明，在帕金森病患者的医学评估和治疗中应考虑焦虑症，并应进一步关注多巴胺能系统在焦虑和恐惧症中的作用。
To study the prevalence and importance of anxiety disorders in patients with idiopathic Parkinson's disease, the authors systematically evaluated 24 parkinsonian patients for the presence of DSM-III-R axis I syndromes. Nine subjects (38%) had a clinically significant current anxiety disorder. Severity of anxiety was not correlated with severity of parkinsonian symptoms, cumulative duration of L-dopa exposure, or current dose of L-dopa. These findings suggest that anxiety disorders should be considered in the medical evaluation and treatment of parkinsonian patients and that further attention should be paid to the role of the dopaminergic system in anxiety and phobic disorders.