Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline.
Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline.
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DOI：
10.14309/ajg.0000000000001680
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发表时间：
2022-04-01
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影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
巴雷特食管（BE）是一种常见的疾病与慢性胃食管反流病。BE是唯一已知的食管腺癌的前体，食管腺癌是一种高度致命的癌症，在过去50年中发病率不断增加。这些修订后的指南实施了建议分级、评估、制定和评价方法，为BE的定义和诊断、BE和食管腺癌的筛查、已知BE患者的监测以及BE及其相关早期肿瘤的医学和内镜治疗提出了建议。自本指南上次迭代以来的重要变化包括扩大BE的可接受筛查方式，包括非内镜方法，放宽短节段BE监测的间隔时间，以及BE内镜治疗中心的容量标准。对于BE伴高度异型增生和BE伴低度异型增生的患者，推荐内镜下根除治疗。我们建议根据基线发育不良程度对成功消融后发育不良BE患者进行结构化监测。由于数据不足，我们无法就化学预防或在常规实践中使用生物标志物提出建议。
Barrett’s esophagus (BE) is a common condition associated with chronic gastroesophageal reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly lethal cancer with an increasing incidence over the last 5 decades. These revised guidelines implement Grading of Recommendations, Assessment, Development, and Evaluation methodology to propose recommendations for the definition and diagnosis of BE, screening for BE and esophageal adenocarcinoma, surveillance of patients with known BE, and the medical and endoscopic treatment of BE and its associated early neoplasia. Important changes since the previous iteration of this guideline include a broadening of acceptable screening modalities for BE to include nonendoscopic methods, liberalized intervals for surveillance of short-segment BE, and volume criteria for endoscopic therapy centers for BE. Were commend endoscopic eradication therapy for patients with BE and high-grade dysplasia and those with BE and low-grade dysplasia. We propose structured surveillance intervals for patients with dysplastic BE after successful ablation based on the baseline degree of dysplasia. We could not make recommendations regarding chemoprevention or use of biomarkers in routine practice due to insufficient data.
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影响因子：
7.6
作者：
Attwood, S. E.;Ell, C.;Lundell, L.
通讯作者：
Lundell, L.
影响因子：
29.4
作者：
Codipilly DC;Chandar AK;Singh S;Wani S;Shaheen NJ;Inadomi JM;Chak A;Iyer PG
通讯作者：
Iyer PG
影响因子：
3.7
作者：
Cook MB;Corley DA;Murray LJ;Liao LM;Kamangar F;Ye W;Gammon MD;Risch HA;Casson AG;Freedman ND;Chow WH;Wu AH;Bernstein L;Nyrén O;Pandeya N;Whiteman DC;Vaughan TL
通讯作者：
Vaughan TL
影响因子：
7.7
作者：
Agarwal, Siddharth;Alshelleh, Mohammad;Iyer, Prasad G.
通讯作者：
Iyer, Prasad G.
影响因子：
9.6
作者：
BARRETT, NR
通讯作者：
BARRETT, NR