Quantifying the effects of exposure to indoor air pollution from biomass combustion on acute respiratory infections in developing countries
Quantifying the effects of exposure to indoor air pollution from biomass combustion on acute respiratory infections in developing countries
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DOI：
10.2307/3454706
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发表时间：
2001-05-01
影响因子：
10.4
通讯作者：
Kammen, DM
中科院分区：
文献类型：
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作者：
Ezzati, M;Kammen, DM
急性呼吸道感染（ARI）是全世界疾病负担的主要原因，与发展中国家接触国内生物质燃料产生的污染物有因果关系。我们使用纵向健康数据，结合对肯尼亚农村2年多实地测量中个人暴露情况的详细监测和估计，来估计生物质燃烧产生的< 10微米直径颗粒物（PM10）的暴露-反应关系。急性呼吸道感染和急性下呼吸道感染呈凹形，增加PM10日均暴露量的函数，暴露量在约1,000-2,000马克杯/米以上时，增加率下降(3)。对发展中国家高接触水平特征的接触-反应关系的首次估计，对影响全世界20多亿人的国际公共卫生政策、能源和燃烧研究以及技术转让工作具有直接和重要的影响。
Acute respiratory infections (ARI) are the leading cause of burden of disease worldwide and have been causally linked with exposure to pollutants from domestic biomass fuels in developing countries. We used longitudinal health data coupled with detailed monitoring and estimation of personal exposure from more than 2 years of field measurements in rural Kenya to estimate the exposure-response relationship for particulates < 10 mum diameter (PM10) generated from biomass combustion. Acute respiratory infections and acute lower respiratory infections are concave, increasing functions of average daily exposure to PM10, with the rate of increase declining for exposures above approximately 1,000-2,000 mug/m(3). This first estimation of the exposure-response relationship for the high-exposure levels characteristic of developing countries has immediate and important consequences for international public health policies, energy and combustion research, and technology transfer efforts that affect more than 2 billion people worldwide.