The biological activity of 5,6-epoxyretinoic acid.
The biological activity of 5,6-epoxyretinoic acid.
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5,6-环氧视黄酸的生物活性。
DOI：
10.1093/jn/110.11.2225
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Deluca,HF
中科院分区：
文献类型：
--
作者：
Zile,MH;Inhorn,RC;Deluca,HF
全反式-5，6-环氧视黄酸促进维生素A缺乏大鼠生长的潜力在25倍剂量范围内进行了评价，采用每日单次腹腔注射。发现5，6-环氧维甲酸的活性为全反式维甲酸的0.5%。讨论了目前的结果与其他工作者以前所获得的结果之间的差异。
The potential of all-trans-5, 6-epoxyretinoic acid to promote growth in vitamin A-deficient rats was evaluated over a 25-fold dose range using single daily intraperitoneal injections. 5, 6-Epoxyretinoic acid was found to be 0.5% as active as all-trans-retinoic acid. The discrepancies between the present results and those obtained previously by other workers are discussed.