CuI-Catalyzed Cross-Coupling of N-Tosylhydrazones with Terminal Alkynes: Synthesis of 1,3-Disubstituted Allenes

CuI-Catalyzed Cross-Coupling of N-Tosylhydrazones with Terminal Alkynes: Synthesis of 1,3-Disubstituted Allenes
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CuI 催化 N-甲苯磺酰腙与末端炔烃的交叉偶联:1,3-二取代丙二烯的合成

DOI:
10.1021/jo3024686
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发表时间:
2013-02-01
影响因子:
3.6
通讯作者:
Wang, Jianbo
Wang, Jianbo
中科院分区:
化学2区
文献类型:
--
作者:
Hossain, Mohammad Lokman;Ye, Fei;Wang, Jianbo

文献摘要

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A CuI-catalyzed synthesis of 1,3-disubstituted allenes from 1-alkynes by the reaction with various N-tosylhydrazones has been developed. This method, which uses readily available starting materials and is operationally simple, offers 1,3-disubstituted allenes in moderate to good yields. The reaction also tolerates various functional groups.