The role of mucoactive agents in the mechanically ventilated patient: a review of the literature
The role of mucoactive agents in the mechanically ventilated patient: a review of the literature
复制标题
DOI：
10.1080/17476348.2017.1359090
复制
发表时间：
2017-01-01
影响因子：
3.9
通讯作者：
Rubio, Edmundo
中科院分区：
文献类型：
--
作者：
Icard, Bradley L.;Rubio, Edmundo
引言：机械通气患者气道分泌物的管理是所有重症监护病房的常规任务。目前的治疗策略主要是基于轶事的经验，而不是统计学evidence.Areas覆盖：这篇评论文章评估的数据，从已发表的试验周围的粘液活性剂和他们的使用在重症患者人群。我们通过EBSCO完成了PUBMED和CINAHL的广泛检索，沿着与Cochran图书馆一起查找所有在危重患者人群中使用粘液活性剂的试验。专家评论：总体而言，粘液活性剂在重症监护病房中的作用是肺重症监护中需要循证推荐的一个领域。我们认为，研究者有很大的机会来评估不同的粘液活性治疗在这一患者群体，并确定其对临床结果的影响。
Introduction: The management of airway secretions in the mechanically ventilated patient is a routine task throughout all intensive care units. The current treatment strategies are primarily based on anecdotal experiences rather than statistical evidence.Areas covered: This review article evaluates the data from published trials surrounding mucoactive agents and their use in the critically ill patient population. We completed an extensive search through PUBMED and CINAHL via EBSCO, along with the Cochran library to find all trials using mucoactive agents in the critically ill patient population.Expert commentary: Overall, the role of mucoactive agents in the intensive care unit is a field within pulmonary critical care that is in need of evidence-based recommendations. We feel that there is great opportunity for investigators to evaluate different mucoactive therapies in this patient population and to determine their effect on clinical outcomes.