Curcacycline B, a cyclic nonapeptide from Jatropha curcas enhancing rotamase activity of cyclophilin

Curcacycline B, a cyclic nonapeptide from Jatropha curcas enhancing rotamase activity of cyclophilin
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DOI:
10.1016/s0040-4039(97)00495-4
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发表时间:
1997-04-21
影响因子:
1.8
通讯作者:
Bodo, B
Bodo, B
中科院分区:
化学4区
文献类型:
--
作者:
Auvin, C;Baraguey, C;Bodo, B

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利用化学降解、LSIMS和2DNMR等方法对从小桐子胶乳中分离得到的环状九肽curcacycline B(1)进行了结构鉴定。姜黄素B显示出增强人亲环素B的旋转异构酶活性。(C)1997年由Elsevier Science Ltd.出版
The structure of curcacycline B (1), a cyclic nonapeptide isolated from Jatropha curcas latex was elucidated by combination of chemical degradation, LSIMS data and 2D NMR experiments. Curcacycline B was shown to enhance the rotamase activity of human cyclophilin B. (C) 1997 Published by Elsevier Science Ltd.