Backfiltration: Past, Present and Future
Backfiltration: Past, Present and Future
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DOI：
10.1159/000333626
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Ronco, Claudio
中科院分区：
文献类型：
--
作者：
Rangel, Armando Vazquez;Kim, Jeong Chul;Ronco, Claudio
反滤已被认为存在于大多数扩散对流疗法中。尽管最初认为这是一种不便，因为它会将透析液中的污染物转运到血液室，但超纯透析液的可用性促使人们重新审视反滤现象，并有可能利用它来进一步增强中分子和大分子的对流清除。这篇综述讨论了反滤的历史，其机制和影响因素，以及随后不同的血液透析技术与增加或减少这种现象的关系。版权所有（C）2011 S. Karger AG，巴塞尔
Backfiltration has been recognized to be present in most diffusive-convective therapies. Although initially considered an inconvenience due to its implications in transport of contaminants in dialysate to the blood compartment, the availability of ultrapure dialysate has prompted a fresh look at the phenomenon of backfiltration with the possibility of exploiting it to further enhance the convective clearance of middle and large molecules. This review discusses the historical aspects of backfiltration, its mechanisms and influencing factors, and subsequently the different hemodialysis techniques in relation to increasing or diminishing this phenomenon. Copyright (C) 2011 S. Karger AG, Basel