International Society for Heart and Lung Transplantation working formulation of a standardized nomenclature for cardiac allograft vasculopathy-2010
International Society for Heart and Lung Transplantation working formulation of a standardized nomenclature for cardiac allograft vasculopathy-2010
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DOI：
10.1016/j.healun.2010.05.017
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发表时间：
2010-07-01
影响因子：
8.9
通讯作者：
Uber, Patricia A.
中科院分区：
文献类型：
--
作者：
Mehra, Mandeep R.;Crespo-Leiro, Maria G.;Uber, Patricia A.
心脏移植物血管病变的发展仍然是心脏移植的阿喀琉斯之踵。不幸的是，心脏移植物血管病变的定义是多种多样的，并没有统一的国际标准的命名这一实体。该共识文件由国际心肺移植委员会委托编写，基于对血管造影、血管内超声成像、微血管功能、心脏同种异体移植组织学、循环免疫标志物、非侵入性成像检测以及基于基因和蛋白质的生物标志物相关可用信息进行批判性分析得出的最佳证据和临床共识。本文件代表了心脏移植物血管病国际命名的工作公式，类似于通过组织学判定心脏移植物排斥反应的系统的发展。J Heart Lung Transplant 2010;29：717-27（C）2010年国际心肺移植学会。All rights reserved.
The development of cardiac allograft vasculopathy remains the Achilles heel of cardiac transplantation. Unfortunately, the definitions of cardiac allograft vasculopathy are diverse, and there are no uniform international standards for the nomenclature of this entity. This consensus document, commissioned by the International Society of Heart and Lung Transplantation Board, is based on best evidence and clinical consensus derived from critical analysis of available information pertaining to angiography, intravascular ultrasound imaging, microvascular function, cardiac allograft histology, circulating immune markers, non-invasive imaging tests, and gene-based and protein-based biomarkers. This document represents a working formulation for an international nomenclature of cardiac allograft vasculopathy, similar to the development of the system for adjudication of cardiac allograft rejection by histology. J Heart Lung Transplant 2010;29:717-27 (C) 2010 International Society for Heart and Lung Transplantation. All rights reserved.