Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
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DOI：
10.1016/j.jaci.2016.10.010
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发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
Boyce JA
中科院分区：
文献类型：
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作者：
Togias A;Cooper SF;Acebal ML;Assa'ad A;Baker JR Jr;Beck LA;Block J;Byrd-Bredbenner C;Chan ES;Eichenfield LF;Fleischer DM;Fuchs GJ 3rd;Furuta GT;Greenhawt MJ;Gupta RS;Habich M;Jones SM;Keaton K;Muraro A;Plaut M;Rosenwasser LJ;Rotrosen D;Sampson HA;Schneider LC;Sicherer SH;Sidbury R;Spergel J;Stukus DR;Venter C;Boyce JA
食物过敏是一个重要的公共卫生问题，因为它影响儿童和成人，它可能是严重的，甚至危及生命，它的患病率可能会增加。从2008年开始，美国国家过敏和传染病研究所（NIAID）与其他组织和倡导团体合作，领导制定了第一个食物过敏诊断和管理的临床指南。最近一项具有里程碑意义的临床试验和其他新出现的数据表明，从婴儿期开始引入含花生的食物可以预防花生过敏。在这些发现的推动下，与25个专业组织、联邦机构和患者权益团体一起，NIAID促进了附录指南的制定，专门针对花生过敏的预防。该附录提供了三个独立的指南，适用于花生过敏发展的不同风险水平的婴儿，供各种各样的卫生保健提供者使用。讨论的主题包括风险类别的定义，适当使用测试（特异性IgE，皮肤点刺试验和口腔食物挑战）以及在卫生保健提供者办公室或家中引入含花生食品的时间和方法。《指南增编》提供了每项建议的背景、理由和证据力度。已经制定了指南，以便在花生过敏风险水平不同的婴儿的饮食中尽早引入含花生的食物。
Food allergy is an important public health problem because it affects children and adults, it may be severe and even life-threatening, and it may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases (NIAID), working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy. Prompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, NIAID facilitated development of Addendum Guidelines to specifically address the prevention of peanut allergy. The Addendum provides three separate guidelines for infants at various risk levels for development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE, skin prick testing, and oral food challenge) and the timing and approaches for introduction of peanut-containing foods in the health care provider’s office or at home. The Addendum Guidelines provide the background, rationale, and strength of evidence for each recommendation. Guidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.