Plasma mineral content in type-2 diabetic patients and their association with the metabolic syndrome
Plasma mineral content in type-2 diabetic patients and their association with the metabolic syndrome
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DOI：
10.1159/000108108
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发表时间：
2007-01-01
影响因子：
3.9
通讯作者：
Martinez-Para, M. C.
中科院分区：
文献类型：
--
作者：
Aguilar, V.;Saavedra, P.;Martinez-Para, M. C.
背景：代谢综合征是一种临床疾病，在西班牙越来越普遍。该综合征包括一组代谢紊乱，如2型糖尿病、高血压、血脂异常和肥胖，其可能与血清水平的变化和某些矿物质元素的不良递送有关。研究方法：本研究试图确定代谢综合征是否可能与92名糖尿病受试者（其中一些患有与代谢综合征相关的某些疾病）和72名对照受试者（Hospital Principe de Asturias，Alcal de Henares，西班牙）中矿物质元素镁、铜、锌、铬和镍的血清水平变化有关。结果如下：结果表明，作为一个群体，与代谢综合征有关的改变确实与所考虑的矿物元素的血液水平的变化有关，尽管仅在铜的情况下记录了统计学上的显著差异。尽管如此，导致该综合征的每种单独成分的矿物质水平呈上升趋势。结论：代谢并发症似乎与某些矿物质水平的改变有关，尤其是铜。版权所有（c）2007 S. Karger AG，巴塞尔。
Background: Metabolic syndrome is a clinical disorder that is becoming more prevalent in Spain. The syndrome encompasses a set of metabolic disorders such as type-2 diabetes mellitus, hypertension, dyslipidemia, and obesity, which may be associated with variations in serum levels and poor delivery of certain mineral elements. Methods: This study attempted to ascertain whether metabolic syndrome might be linked to alterations in serum levels of the mineral elements magnesium, copper, zinc, chromium, and nickel in a population of 92 diabetic subjects, some suffering from certain conditions associated with the metabolic syndrome, and 72 control subjects ( Hospital Principe de Asturias, Alcal de Henares, Spain). Results: The results indicated that as a group the alterations implicated in metabolic syndrome were indeed associated with variations in blood levels of the mineral elements considered, though statistically significant differences were recorded only in the case of copper. Still, trends in mineral levels for each of the separate components contributing to the syndrome tended to increase. Conclusion: Metabolic complications appear to be associated with alterations in the levels of some minerals, especially copper. Copyright (c) 2007 S. Karger AG, Basel.