Heart rate variability.
Heart rate variability.
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DOI：
10.1016/b978-0-444-53491-0.00031-6
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发表时间：
2013-01-01
影响因子：
--
通讯作者：
Zareba, Wojciech
中科院分区：
文献类型：
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作者：
Cygankiewicz, Iwona;Zareba, Wojciech
心率变异性（HRV）提供了对自主神经系统张力的间接了解，并作为心血管风险的标志物具有公认的作用。近几十年来，心率变异性评估作为一种诊断工具，在检测自主神经功能障碍和预测预后的几种神经系统疾病带来了越来越多的兴趣。HRV的简单标志物的床边分析以及包括时域、频域和非线性分析的更复杂的HRV分析两者已被证明检测几种神经系统疾病中的早期自主神经受累。此外，在神经系统疾病患者中，HRV参数的改变与心血管风险相关，包括突发心脏病风险。本章旨在回顾HRV分析在糖尿病、中风、多发性硬化、肌营养不良、帕金森病和癫痫的临床和预后应用。
Heart rate variability (HRV) provides indirect insight into autonomic nervous system tone, and has a well-established role as a marker of cardiovascular risk. Recent decades brought an increasing interest in HRV assessment as a diagnostic tool in detection of autonomic impairment, and prediction of prognosis in several neurological disorders. Both bedside analysis of simple markers of HRV, as well as more sophisticated HRV analyses including time, frequency domain and nonlinear analysis have been proven to detect early autonomic involvement in several neurological disorders. Furthermore, altered HRV parameters were shown to be related with cardiovascular risk, including sudden cardiac risk, in patients with neurological diseases. This chapter aims to review clinical and prognostic application of HRV analysis in diabetes, stroke, multiple sclerosis, muscular dystrophies, Parkinson's disease and epilepsy.