Drinking saccharin increases food intake and preference--I. Comparison with other drinks.
Drinking saccharin increases food intake and preference--I. Comparison with other drinks.
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饮用糖精会增加食物摄入量和偏好——I。
DOI：
10.1016/0195-6663(89)90064-0
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发表时间：
1989
期刊：
影响因子：
5.4
通讯作者：
Friedman,MI
中科院分区：
文献类型：
--
作者：
Tordoff,MG;Friedman,MI
为探讨糖精溶液对大鼠进食量和食欲的影响，对自由喂养的大鼠8~10次给予风味食品和饮料2 h。与不同风味食物和只喝水的试验相比，饮用0.2%糖精或0.45%氯化钠的食物摄入量增加，饮用1%杏仁提取物不影响食物摄入量，饮用10%葡萄糖则减少食物摄入量。食物偏好是在同时获得两种口味食物的选择测试中评估的，饮用0.2%的糖精或10%的葡萄糖会增加食物偏好，而饮用1%的杏仁提取物或0.45%的氯化钠不会影响食物偏好。这些结果与糖精溶液的口服和水合特性相结合增加食物摄入量的可能性是一致的。糖精的甜味可能是它对食物偏好产生影响的原因。
To examine the orosensory and postingestive effects of saccharin solution on food intake and food preference, freely feeding rats were given flavored food to eat and a solution to drink for 2 h on eight to ten occasions. Relative to trials with a different flavored food and only water to drink, food intake was increased by drinking 0.2% saccharin or 0.45% NaCl, unaffected by drinking 1% almond extract, and decreased by drinking 10% glucose. Food preference, which was assessed in a choice test with simultaneous access to the two flavored foods, was increased by drinking 0.2% saccharin or 10% glucose and unaffected by drinking 1% almond extract or 0.45% NaCl. These results are consistent with the possibility that a combination of the oral and hydrational properties of saccharin solution increase food intake. Saccharin's sweet taste may be responsible for its effects on food preference.