Overview of quantitative susceptibility mapping

Overview of quantitative susceptibility mapping
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DOI:
10.1002/nbm.3569
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发表时间:
2017-04-01
期刊:
影响因子:
2.9
通讯作者:
Reichenbach, Juergen R.
Reichenbach, Juergen R.
中科院分区:
医学3区
文献类型:
--
作者:
Deistung, Andreas;Schweser, Ferdinand;Reichenbach, Juergen R.

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磁化率描述了材料对所施加磁场的可磁化性,并且代表MRI领域中的重要参数。随着最近引入的定量磁化率映射(QSM)及其概念扩展到磁化率张量成像(STI)的方法,这一重要物理量的非侵入性评估已成为可能与MRI。这两种方法解决了不适定的反问题,以确定磁化率从局部磁场。虽然QSM允许从单次测量中提取体磁化率的空间分布,但STI允许磁化率各向异性的量化,但需要对象相对于主静磁场的不同取向的多次测量。在这篇综述中,我们简要概括了QSM和STI的基本理论基础,以及利用MRI相位数据表征磁化率的计算策略。在第二部分中,我们提供了一个概述,目前的方法和临床应用QSM的重点是脑成像。版权所有(C)2016约翰威利父子有限公司
Magnetic susceptibility describes the magnetizability of a material to an applied magnetic field and represents an important parameter in the field of MRI. With the recently introduced method of quantitative susceptibility mapping (QSM) and its conceptual extension to susceptibility tensor imaging (STI), the non-invasive assessment of this important physical quantity has become possible with MRI. Both methods solve the ill-posed inverse problem to determine the magnetic susceptibility from local magnetic fields. Whilst QSM allows the extraction of the spatial distribution of the bulk magnetic susceptibility from a single measurement, STI enables the quantification of magnetic susceptibility anisotropy, but requires multiple measurements with different orientations of the object relative to the main static magnetic field. In this review, we briefly recapitulate the fundamental theoretical foundation of QSM and STI, as well as computational strategies for the characterization of magnetic susceptibility with MRI phase data. In the second part, we provide an overview of current methodological and clinical applications of QSM with a focus on brain imaging. Copyright (C) 2016 John Wiley & Sons, Ltd.