Tablet: Visualizing Next-Generation Sequence Assemblies and Mappings
Tablet: Visualizing Next-Generation Sequence Assemblies and Mappings
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DOI：
10.1007/978-1-4939-3167-5_14
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发表时间：
2016-01-01
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影响因子：
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通讯作者：
Marshall, David
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文献类型：
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作者：
Milne, Iain;Bayer, Micha;Marshall, David
本章旨在成为使用平板电脑可视化下一代/第二代（NGS）测序数据的实用指南。NGS数据的制作越来越频繁，每年的数据量也越来越大。因此，拥有能够使生物学家和生物信息学家理解并获得对其数据的关键见解的工具变得越来越重要。可视化可以在这些数据的探索中发挥关键作用，并有助于序列组装和单核苷酸多态性（SNP）等特征的可视化验证。我们的目标是展示几个用例，这些用例展示了平板电脑在视觉上突出显示NGS数据中可能出现的各种感兴趣情况的能力。
This chapter is designed to be a practical guide to using Tablet for the visualization of next/second-generation (NGS) sequencing data. NGS data is being produced more frequently and in greater data volumes every year. As such, it is increasingly important to have tools which enable biologists and bioinformaticians to understand and gain key insights into their data. Visualization can play a key role in the exploration of such data as well as aid in the visual validation of sequence assemblies and features such as single nucleotide polymorphisms (SNPs). We aim to show several use cases which demonstrate Tablet's ability to visually highlight various situations of interest which can arise in NGS data.