Quantification of shoaling behaviour in zebrafish (Danio rerio)
Quantification of shoaling behaviour in zebrafish (Danio rerio)
复制标题
DOI：
10.1016/j.bbr.2007.07.007
复制
发表时间：
2007-12-03
影响因子：
2.7
通讯作者：
Gerlai, Robert
中科院分区：
文献类型：
--
作者：
Miller, Noam;Gerlai, Robert
斑马鱼一直是发育生物学家的最爱，已经为这个物种开发了许多遗传工具。近年来，斑马鱼已成为神经科学家和行为科学家越来越受欢迎的研究对象。斑马鱼的一个典型特征是浅滩化，个体形成一个紧密的群体，鱼在其中一起游泳。社会行为的生物学机制是复杂的，在脊椎动物中还没有得到很好的理解，而斑马鱼，由于其高度的社会性和为它开发的遗传工具，可能是一个很好的动物模型，这些机制可能会被研究。改进行为量化方法将促进这一领域的研究。我们描述了一个自定义的软件应用程序，可以精确量化的几个参数的组凝聚力在斑马鱼。我们还提出了三个实验的例子来说明我们的方法的使用，并显示如何组凝聚力的变化，以应对操纵的环境。(C)2007 Elsevier B.V.保留所有权利。
Zebrafish has been a favourite of developmental biologists and numerous genetic tools have been developed for this species. In recent years, zebrafish has become an increasingly popular subject of neuroscientists and behavioural scientists. One of the typical characteristics of zebrafish is shoaling, individuals forming a tight group in which fish swim together. The biological mechanisms of social behaviours are complex and not well understood in vertebrates, and zebrafish, due to its highly social nature and the genetic tools developed for it, may represent an excellent animal model with which these mechanisms may be studied. Improvement of behavioural quantification methods would facilitate research in this area. We describe a custom software application that allows the precise quantification of several parameters of group cohesion in zebrafish. We also present three experimental examples to illuminate the use of our methodology, and show how group cohesion changes in response to manipulations of the environment. (C) 2007 Elsevier B.V. All rights reserved.