Repeated tourniquet testing as a diagnostic tool in dengue infection.
Repeated tourniquet testing as a diagnostic tool in dengue infection.
复制标题
重复止血带测试作为登革热感染的诊断工具。
DOI：
--
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
S. Mangalam
中科院分区：
文献类型：
--
作者：
O. Norlijah;A. Khamisah;A. Kamarul;M. Paeds;S. Mangalam
对反复标准止血带试验作为登革热感染诊断指标进行了前瞻性评价。其中包括根据世界卫生组织（世卫组织）标准因临床怀疑感染登革热而被吉隆坡一家儿童医院收治的患者。入院后对79例患者每日采用标准止血带方法。其余14名受试者为阴性。血清学确诊病例58例，不确定病例4例，血清学阴性17例。在诊断分类方面，13人患有登革热，49人患有登革出血热，17人患有非登革热感染。止血带试验的敏感性为82.8%，特异性为23.5%。阳性预测值（PPV） 78.7%，阴性预测值（NPV） 28.6%。此外，止血带试验有助于五分之一的DHF患者的诊断，这些患者的唯一出血表现是止血带试验阳性。在医院环境中，止血带试验似乎对登革热感染/登革出血热的诊断没有什么帮助。根据世卫组织的建议，反复进行的止血带阳性试验作为登革热感染的初步筛查试验在临床上是有用的。然而，它不是很具体，有很高的假阳性率。
Prospective evaluation of repeated standard tourniquet testing as a diagnostic indicator of dengue infection was done. Included were patients admitted to a children's hospital in Kuala Lumpur on a clinical suspicion of dengue infection based on the World Health Organization (WHO) criteria. A standard method of tourniquet was performed on 79 patients on a daily basis following admission. subjects and negative in the remaining 14 subjects. Fifty-eight subjects were serologically confirmed cases, 4 indeterminate and the remaining 17 subjects had negative serology. For diagnostic classification, 13 had dengue fever, 49 with dengue haemmorhagic fever (DHF) while 17 had non-dengue infection. The sensitivity and specificity of the tourniquet test was 82.8% and 23.5% respectively. The positive predictive value (PPV) was 78.7% while the negative predictive value (NPV) was 28.6%. In addition, the tourniquet test aided in the diagnosis of one-fifth of patients with DHF, who presented with a positive tourniquet test as the only bleeding manifestation. It seems that in a hospital setting, the tourniquet test adds little to the diagnosis of dengue infection/DHF. A positive tourniquet test, repeatedly performed, was found clinically useful as a preliminary screening test in dengue infection as recommended by WHO. However, it was not very specific and had a high false positive rate.
影响因子：
6.4
作者：
Kalayanarooj, S;Vaughn, DW;Ennis, FA
通讯作者：
Ennis, FA