The genome sequence of Blochmannia floridanus:: Comparative analysis of reduced genomes
The genome sequence of Blochmannia floridanus:: Comparative analysis of reduced genomes
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DOI：
10.1073/pnas.1533499100
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发表时间：
2003-08-05
影响因子：
11.1
通讯作者：
Moya, A
中科院分区：
文献类型：
--
作者：
Gil, R;Silva, FJ;Moya, A
细菌共生体在昆虫中广泛存在，可能是它们进化成功的关键因素之一。我们提出了完整的基因组序列Blochmannia floridanus，木蚁的主要内共生体。虽然这些蚂蚁以复杂的饮食为食，但这种共生关系很可能具有营养基础：Blochmannia能够为宿主提供氮和硫化合物，同时利用宿主的代谢机制。值得注意的是，这些细菌缺乏所有已知的参与复制起始的基因（dnaA，priA和recA）。对一组保守的蛋白质编码基因的系统发育分析表明，BI. floridanus在遗传学上与Buchnera aphidicola和Wiggiesperiaglossinidia相关，这两种内共生细菌的完整基因组迄今已被测序。对来自昆虫内共生细菌的五个已知基因组的比较分析显示，它们只有313个基因，这个数字可能接近维持内共生生命所必需的最小基因组。
Bacterial symbioses are widespread among insects, probably being one of the key factors of their evolutionary success. We present the complete genome sequence of Blochmannia floridanus, the primary endosymbiont of carpenter ants. Although these ants feed on a complex diet, this symbiosis very likely has a nutritional basis: Blochmannia is able to supply nitrogen and sulfur compounds to the host while it takes advantage of the host metabolic machinery. Remarkably, these bacteria lack all known genes involved in replication initiation (dnaA, priA, and recA). The phylogenetic analysis of a set of conserved protein-coding genes shows that BI. floridanus is phylogenetically related to Buchnera aphidicola and Wiggiesworthia glossinidia, the other endosymbiotic bacteria whose complete genomes have been sequenced so far. Comparative analysis of the five known genomes from insect endosymbiotic bacteria reveals they share only 313 genes, a number that may be close to the minimum gene set necessary to sustain endosymbiotic life.