Observational versus experimental studies: what's the evidence for a hierarchy?
Observational versus experimental studies: what's the evidence for a hierarchy?
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DOI：
10.1602/neurorx.1.3.341
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发表时间：
2004-07-01
期刊：
影响因子：
--
通讯作者：
Concato, John
中科院分区：
文献类型：
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作者：
Concato, John
循证医学的原则包括强调研究设计的层次性(即研究架构)。通常，一个单独的随机对照试验被认为提供了“真相”，而任何观察性研究的结果都被怀疑。这篇论文描述了与这种僵化的评估研究设计质量的方法相矛盾和不鼓励的信息。除非发展出一种更平衡的策略，否则新的方法权威主张可能与传统的医学权威主张一样存在问题，后者受到了循证医学支持者的批评。
The tenets of evidence-based medicine include an emphasis on hierarchies of research design (i.e., study architecture). Often, a single randomized, controlled trial is considered to provide "truth," whereas results from any observational study are viewed with suspicion. This paper describes information that contradicts and discourages such a rigid approach to evaluating the quality of research design. Unless a more balanced strategy evolves, new claims of methodological authority may be just as problematic as the traditional claims of medical authority that have been criticized by proponents of evidence-based medicine.