Niche Partitioning of Borrelia burgdorferi and Borrelia miyamotoi in the Same Tick Vector and Mammalian Reservoir Species
Niche Partitioning of Borrelia burgdorferi and Borrelia miyamotoi in the Same Tick Vector and Mammalian Reservoir Species
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DOI：
10.4269/ajtmh.2009.09-0208
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发表时间：
2009-12-01
影响因子：
3.3
通讯作者：
Tsao, Jean I.
中科院分区：
文献类型：
--
作者：
Barbour, Alan G.;Bunikis, Jonas;Tsao, Jean I.
莱姆疏螺旋体病病原体伯氏疏螺旋体和回归热群种宫本疏螺旋体在美国同时出现。我们使用物种特异性的定量聚合酶链反应来研究康涅狄格州一个地点的白白鼠和寻找宿主的肩突硬蜱若虫的血液和皮肤中的这两个物种。伯氏疏螺旋体或宫本疏螺旋体菌血症分别在若虫或幼虫活动最活跃的时期最为普遍。皮肤活检中伯氏疏螺旋体的出现频率比宫本伯氏疏螺旋体高 30 倍，并且小鼠皮肤中的伯氏疏螺旋体密度高于血液中的伯氏疏螺旋体，而血液中的伯氏疏螺旋体密度则高于皮肤中的伯氏疏螺旋体。在对北部 11 个州的寻主若虫的调查中，伯氏疏螺旋体和宫本疏螺旋体的平均感染率分别约为 0.20 和 0.02。白种伯氏杆菌或肩胛伯氏杆菌与伯氏疏螺旋体和宫本伯氏杆菌的共同感染并不比随机预期的更常见。
The Lyme borreliosis agent Borrelia burgdorferi and the relapsing fever group species Borrelia miyamotoi co-occur in the United States. We used species-specific, quantitative polymerase chain reaction to study both species in the blood and skin of Peromyscus leucopus mice and host-seeking Ixodes scapularis nymphs at a Connecticut site. Bacteremias with R burgdorferi or B. miyamotoi were most prevalent during periods of greatest activity for nymphs or larvae, respectively. Whereas B. burgdorferi was 30-fold more frequent than B. miyamotoi in skin biopsies and mice had higher densities of B. burgdorferi densities in the skin than in the blood, B. miyamotoi densities were higher in blood than skin. In a survey of host-seeking nymphs in 11 northern states, infection prevalences for B. burgdorferi and B. miyamotoi averaged similar to 0.20 and similar to 0.02, respectively. Co-infections of P. leucopus or L. scapularis with both B. burgdorferi and B. miyamotoi were neither more nor less common than random expectations.