Protective Effects of Passively Transferred Merozoite-Specific Antibodies against Theileria equi in Horses with Severe Combined Immunodeficiency
Protective Effects of Passively Transferred Merozoite-Specific Antibodies against Theileria equi in Horses with Severe Combined Immunodeficiency
复制标题
被动转移裂殖子特异性抗体对严重联合免疫缺陷马马泰勒虫的保护作用
DOI：
10.1128/cvi.05301-11
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发表时间：
2011
影响因子：
--
通讯作者：
D. Knowles
中科院分区：
文献类型：
--
作者：
R. Mealey;L. Kappmeyer;M. Ueti;B. Wagner;D. Knowles
将马泰勒虫免疫血浆输注给患有严重联合免疫缺陷的年轻马（马驹）。尽管所有马驹在用同源T.马裂殖子稳定，出现寄生虫血症峰值的时间延迟。保护作用与被动转移裂殖子特异性IgG3的优势相关。
ABSTRACT Theileria equi immune plasma was infused into young horses (foals) with severe combined immunodeficiency. Although all foals became infected following intravenous challenge with homologous T. equi merozoite stabilate, delayed time to peak parasitemia occurred. Protective effects were associated with a predominance of passively transferred merozoite-specific IgG3.