Essential Oil Olfactory Test: Comparison of Affordable Rapid Olfaction Measurement Array (AROMA) to Sniffin' Sticks 12.
Essential Oil Olfactory Test: Comparison of Affordable Rapid Olfaction Measurement Array (AROMA) to Sniffin' Sticks 12.
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DOI：
10.1177/2473974x20962464
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发表时间：
2020-10
期刊：
影响因子：
1.5
通讯作者：
Villwock JA
中科院分区：
文献类型：
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作者：
Li J;Palmer G;Shankar S;Villwock MR;Chiu AG;Sykes KJ;Villwock JA
为了进一步证明可负担得起的快速嗅觉测量阵列（AROMA）的有效性，一种基于精油的气味测试，并将其与Sniffin' Sticks 12测试（SST 12）进行比较。前瞻性横断面研究。学术医疗中心。研究招募了50名无鼻窦疾病的健康个体。AROMA之前已经通过了宾夕法尼亚大学生物识别测试的验证。目前的研究测试了另外2种更高的浓度，以提高检测嗅觉储备的能力。健康受试者完成了AROMA、SST 12、鼻-鼻窦结果测试（SNOT-22）和嗅觉障碍问卷（QoD）。使用斯皮尔曼相关性评价AROMA、SST、SNOT-22和QoD。AROMA具有较强的重测信度（r = 0.757，P <0.01）。AROMA与SST 12呈中度相关（ρ = 0.412，P <0.01）。年龄和SNOT-22与AROMA显著相关（P < .05）（分别为ρ =-0.547，-0.331），年龄与SST弱相关（ρ =-0.377，P < .01）。正确率中位数如下：SST 12识别率为92%; AROMA检测率为90%; AROMA识别率为81%。在1×、2×、4×和8×浓度下，AROMA气味识别的中位正确率分别为64%、75%、92%和92%。AROMA与SST 12有中度相关性。AROMA比SST 12与年龄和SNOT-22的相关性更强。AROMA与主观嗅觉状态的更强相关性、低成本和适应性可能有助于消除临床常规嗅觉测试的障碍。
To further demonstrate the validity of Affordable Rapid Olfaction Measurement Array (AROMA), an essential oil−based smell test, and compare it to the Sniffin’ Sticks 12 Test (SST12). Prospective cross-sectional study. Academic medical center. Fifty healthy individuals without sinonasal disease were recruited to the study. AROMA has been previously validated against the University of Pennsylvania Smell Identification Test. The current study tests 2 additional higher concentrations to increase the ability to detect olfactory reserve. Healthy participants completed AROMA, SST12, Sino-Nasal Outcome Test (SNOT-22), and Questionnaire of Olfactory Disorders (QoD). Spearman correlations were used to evaluate AROMA, SST, SNOT-22, and QoD. AROMA demonstrated strong test-retest reliability (r = 0.757, P < .01). AROMA showed a moderate correlation to SST12 (ρ = 0.412, P < .01). Age and SNOT-22 were significantly correlated (P < .05) with AROMA (ρ = −0.547, −0.331, respectively), and age was weakly correlated with SST (ρ = −0.377, P < .01). Median percent correct scores were as follows: SST12 identification, 92%; AROMA detection, 90%; and AROMA identification, 81%. Median correct odor identification of AROMA concentrations at 1×, 2×, 4×, and 8× were 64%, 75%, 92%, and 92%, respectively. AROMA has a moderate correlation with SST12. AROMA is more strongly correlated than SST12 to age and SNOT-22. AROMA’s stronger correlation with subjective olfactory status, low cost, and adaptability may help remove barriers to routine olfactory testing in the clinic.