Microbial contamination and preservative capacity of some brands of cosmetic creams
Microbial contamination and preservative capacity of some brands of cosmetic creams
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某些品牌美容霜的微生物污染和防腐能力
DOI：
10.4314/tjpr.v2i2.14604
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Ijoma Igwe
中科院分区：
文献类型：
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作者：
P. G. Hugbo;A. Onyekweli;Ijoma Igwe
目的：化妆品和外用产品不需要无菌，但在使用过程中可能含有低水平的微生物负荷。本研究旨在确定和比较市场上销售的商业化妆品和实验室制备的水性乳膏中微生物污染物的水平和类型及其在使用时的防腐能力。方法：从贝宁市的公开市场随机购买10种品牌的市售化妆品霜剂和乳液。还制备了水性乳膏。评价了它们的细菌和真菌负荷以及类型。通过用洗过并表征的葡萄球菌分离株挑战乳膏和洗剂来评价防腐能力。金黄色葡萄球菌和活菌计数通过表面活菌法进行。用试验微生物对制备的水性乳膏进行类似的挑战。结果：所有产品均受到不同程度的污染。葡萄球菌和其它革兰氏阳性球菌占绝大多数，革兰氏阴性菌很少。烟曲霉属、青霉属和微孢子菌属。葡萄球菌挑战试验（再感染）。金黄色葡萄球菌显示商业产品具有低的抑制细菌增殖的能力，例如在使用中污染期间可能遇到的。结论：评价的商业化妆品乳膏和乳液通常不符合官方专论中规定的微生物限度标准。此类产品可能对消费者的健康状况以及产品的稳定性产生不利影响。
Purpose: Cosmetic and topical products need not be sterile but may contain low levels of microbial load during use. This study was conducted to determine and compare the level and type of microbial contaminants in commercial cosmetic products sold in the market and a laboratory prepared aqueous cream and their preservative capacities while in use. Methods: Ten brands of commercially available cosmetic creams and lotions were randomly purchased from the open markets in Benin City. Aqueous Cream was also prepared. Their bacterial and fungal loads as well as types were evaluated. Preservative capacity was evaluated by challenging the creams and lotions with washed and characterized isolates of Staph. aureus and viable counting was performed by the surface viable method. The prepared aqueous cream was similarly challenged with the test organism. Results: All the products were contaminated to varying degrees. Staphylococci and other gram-positive cocci were the most preponderant; gram-negative isolates were hardly found. Fungal contaminants consisted largely of Asp. fumigatus, Penicillium and Microsporium species. Challenge test (re-infection) with Staph. aureus revealed the commercial products as having low capacity for suppressing bacterial proliferation such as may be encountered during in ‐ use contamination. Conclusion: Commercial cosmetic creams and lotions evaluated did not generally meet the standards for microbial limits as specified in official monographs. Such products can adversely affect health status of consumers as well as the stability profiles of the products.