Immunosuppressive Extracellular Vesicles in CLL.
Immunosuppressive Extracellular Vesicles in CLL.
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CLL 中的免疫抑制细胞外囊泡。
DOI:
10.1158/2643-3230.bcd-22-0161
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发表时间:
2023
影响因子:
11.2
通讯作者:
Guo,Wei
中科院分区:
文献类型:
--
作者:
Zhong,Wenqun;Guo,Wei
Cancer cells need to evade the immune system for their progression. In this issue of Blood Cancer Discovery, Gargiulo and colleagues report that in a mouse model of chronic lymphocytic leukemia, small extracellular vesicles inhibit antitumor immunity by altering CD8 T-cell transcriptome, proteome, and metabolome. See related article by Gargiulo et al., p. 54 (9).