Immunosuppressive Extracellular Vesicles in CLL.

Immunosuppressive Extracellular Vesicles in CLL.
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CLL 中的免疫抑制细胞外囊泡。

DOI:
10.1158/2643-3230.bcd-22-0161
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发表时间:
2023
影响因子:
11.2
通讯作者:
Guo,Wei
Guo,Wei
中科院分区:
--
文献类型:
--
作者:
Zhong,Wenqun;Guo,Wei

文献摘要

相似文献

癌细胞需要逃避免疫系统才能进展。在本期《血癌发现》杂志上,Gargiulo及其同事报道,在慢性淋巴细胞白血病的小鼠模型中,细胞外小泡通过改变CD8 T细胞转录组、蛋白质组和代谢组来抑制抗肿瘤免疫。见Gargiulo等人的相关文章,第54(9)页。
Cancer cells need to evade the immune system for their progression. In this issue of Blood Cancer Discovery, Gargiulo and colleagues report that in a mouse model of chronic lymphocytic leukemia, small extracellular vesicles inhibit antitumor immunity by altering CD8 T-cell transcriptome, proteome, and metabolome. See related article by Gargiulo et al., p. 54 (9).